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• WB检测之后发现有重链的干扰，应该如何处理？

  观察重链和轻链条带的深浅，如果轻链颜色更深，说明抗体特异性良好。需要对样本和抗体进行减量，以起到去除杂带的作用。

本产品已在(54)种出版物中被引用

• NEK2 induces autophagy‐mediated bortezomib resistance by stabilizing Beclin‐1 in multiple myeloma

  作者：J Xia, Y He, B Meng 杂志名称：Molecular Oncology IF：6

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• Combination of PARP inhibitor and CDK4/6 inhibitor modulates cGAS/STING‐dependent therapy‐induced senescence and provides “one‐two punch” opportunity

  作者：T Wang, W Liu, Q Shen, R Tao, C Li, Q Shen 杂志名称：Cancer Science IF：6

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• SARS-CoV-2 ORF3a positively regulates NF-κB activity by enhancing IKKβ-NEMO interaction

  作者：Nie, Ying, et al. 杂志名称：Virus Research IF：5

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• Enhancer of zeste homolog 2 facilitates phenotypic transition of vascular smooth muscle cells leading to aortic aneurysm/dissection

  作者：Xue, Shishan, et al 杂志名称： Experimental and Therapeutic Medicine IF：3

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• 7‑Difluoromethyl‑5, 4'‑dimethoxygenistein exerts anti‑angiogenic effects on acute promyelocytic leukemia HL‑60 cells by inhibiting the TLR4/NF‑κB signaling pathway

  作者：X Xiang, L Li, P Bo 杂志名称：Molecular Medicine Reports IF：2

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• The CH24H metabolite, 24HC, blocks viral entry by disrupting intracellular cholesterol homeostasis

  作者：Yuan, Yueming, et al. 杂志名称：Redox Biology IF：5

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• DCAF13 inhibits the p53 signaling pathway by promoting p53 ubiquitination modification in lung adenocarcinoma

  作者：Shan Wei, Jing Xing, Jia Chen 杂志名称：Journal of Experimental & Clinical Cancer Research IF：11

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• Angiopoietin-like 4 promotes angiogenesis and neurogenesis in a mouse model of acute ischemic stroke

  作者：Z Qiu, J Yang, G Deng 杂志名称：Brain Research Bulletin IF：5

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• Exosomes derived from bone marrow mesenchymal stem cells protect the injured spinal cord by inhibiting pericyte pyroptosis

  作者：Zhou Y, Wen LL, Li YF, Wu KM, Duan RR, Yao YB, Jing LJ, Gong Z, Teng JF, Jia YJ, 杂志名称：Neural Regen Res IF：3

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• The Nucleoprotein and Phosphoprotein of Peste des Petits Ruminants Virus Inhibit Interferons Signaling by Blocking the JAK-STAT Pathway

  作者：P Li, Z Zhu, X Zhang, W Dang, L Li, X Du, M Zhang 杂志名称：Viruses IF：4

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• MiR-375 impairs the invasive capabilities of hepatoma cells by targeting HIF1α under hypoxia

  作者：Chun Wang · Jie Luo · Zhihang Chen 杂志名称：Digestive Diseases and Sciences IF：3

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• MST4 kinase suppresses gastric tumorigenesis by limiting YAP activation via a non-canonical pathway

  作者：L An, P Nie, M Chen 杂志名称：Journal of Experimental Medicine IF：10

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• Rapamycin protects against aristolochic acid nephropathy in mice by potentiating mammalian target of rapamycin‑mediated autophagy

  作者：Lin F, Liu Y, Tang L, Xu X, Zhang X, Song Y, Chen B, Ren Y, Yang X, 杂志名称：Mol Med Rep IF：2

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• Immune evasion strategy involving propionylation by the KSHV interferon regulatory factor 1 (vIRF1)

  作者：Shi, Jiale, et al. 杂志名称：PLoS Pathogens IF：7

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• Synthetic dual hormone-responsive promoters enable engineering of plants with broad-spectrum resistance

  作者：X Li, G Niu, Y Fan, W Liu, Q Wu, C Yu, J Wang 杂志名称：Plant Communications IF：10

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• Immune evasion strategy involving propionylation by the KSHV interferon regulatory factor 1 (vIRF1)

  作者：Shi, Jiale, et al. 杂志名称：PLoS Pathogens IF：7

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• DCAF13 inhibits the p53 signaling pathway by promoting p53 ubiquitination modification in lung adenocarcinoma

  作者：Wei S, **ng J, Chen J 杂志名称：Journal of Experimental & Clinical Cancer Research IF：2

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• AICAR, an AMP-Activated ProteinKinase Activator,Ameliorates Acuteancreatitis-Associated Liver InjuryPartially Through Nrf2-MediatedAntioxidant Effects and Inhibition ofNLRP3 lnflammasome Activation

  作者：W Huang, Q Shi, W Liu 杂志名称：Frontiers in Pharmacology IF：6

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• Coupling of Slack and NaV1.6 sensitizes Slack to quinidine blockade and guides anti-seizure strategy development

  作者：T Yuan, Y Wang, Y Jin, S Xu, H Zhang, Q Chen, N Li 杂志名称：biorxiv IF：

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• SIRT6-PARP1 is involved in HMGB1 polyADP-ribosylation and acetylation and promotes chemotherapy-induced autophagy in leukemia

  作者：Q Kong, Y Li, Q Liang 杂志名称：Cancer Biology &Therapy IF：3

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• Mitochondrial dysfunction induces NLRP3 inflammasome activation during cerebral ischemia/reperfusion injury

  作者：Zhe Gong, Jingrui Pan, et al 杂志名称：Journal of Neuroinflammation IF：6

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• N-Linked Glycosylation and Expression of Duck Plague Virus pUL10 Promoted by pUL49. 5

  作者：C Li, M Wang, A Cheng, Y Wu, B Tian 杂志名称：Microbiology Spectrum IF：4

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• Enhancer of zeste homolog 2 facilitates phenotypic transition of vascular smooth muscle cells leading to aortic aneurysm/dissection

  作者：S Xue, S Leng, F Zhang 杂志名称：Experimental and Therapeutic Medicine IF：6

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• MiR-21-3p Promotes Hepatocellular Carcinoma Progression via SMAD7/YAP1 Regulation

  作者：Y Hong, M Ye, F Wang 杂志名称：Frontiers in Oncology IF：4

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• Ang-(1–7)/Mas axis ameliorates bleomycin-induced pulmonary fibrosis in mice via restoration of Nox4-Nrf2 redox homeostasis

  作者：Sheng M, Li Q, Huang W 杂志名称：European Journal of Pharmacology IF：18

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• SNX32 is a host restriction factor that degrades African swine fever virus CP204L via the RAB1B-dependent autophagy pathway

  作者：Yang, Wenping, et al 杂志名称：Journal of Virology IF：5

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• F0F1 ATP synthase regulates extracellular calcium influx in human neutrophils by interacting with Cav2.3 and modulates neutrophil accumulation in the lipopolysaccharide-challenged lung

  作者：B Zhu, Z Feng, Y Guo 杂志名称：Cell Communication and Signaling IF：5

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• AICAR, an AMP-Activated ProteinKinase Activator,Ameliorates Acuteancreatitis-Associated Liver InjuryPartially Through Nrf2-MediatedAntioxidant Effects and Inhibition ofNLRP3 lnflammasome Activation

  作者：W Huang, Q Shi, W Liu 杂志名称：Frontiers in Pharmacology IF：6

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• Synthetic dual hormone-responsive promoters enable engineering of plants with broad-spectrum resistance

  作者：X Li, G Niu, Y Fan, W Liu, Q Wu, C Yu, J Wang 杂志名称：Plant Communications IF：10

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• S1P/S1PR3 axis promotes aerobic glycolysis by YAP/c-MYC/PGAM1 axis in osteosarcoma

  作者：Yifei Shen, Shujie Zhao, Shenyu Wang, et al 杂志名称：EBioMedicine IF：3

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• FTO promotes innate immunity by controlling NOD1 expression via m6A-YTHDF2 manner in teleost

  作者：Geng S, Zheng W, Zhao Y, et al. 杂志名称：Iscience IF：6

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• Nuclear localization signal in TRIM22 is essential for inhibition of type 2 porcine reproductive and respiratory syndrome virus replication in MARC-145 cells

  作者：H Jing, R Tao, N Dong, S Cao, Y Sun, W Ke, Y Li 杂志名称：Virus Genes, October 2019, Volume 55, Issue 5, pp 660–672 IF：2

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• The CH24H metabolite, 24HC, blocks viral entry by disrupting intracellular cholesterol homeostasis

  作者：Yuan, Yueming, et al. 杂志名称：Redox Biology IF：11

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• Global screening of LUBAC and OTULIN interacting proteins by human proteome microarray

  作者：Zhou L, Ge Y, Fu Y, Wu B, Zhang Y, Li L, Cui CP, Wang S, Zhang L 杂志名称：Front Cell Dev Biol IF：5

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• Coupling of Slack and NaV1.6 sensitizes Slack to quinidine blockade and guides anti-seizure strategy development

  作者：T Yuan, Y Wang, Y Jin, S Xu, H Zhang, Q Chen, N Li 杂志名称：biorxiv IF：

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• NTF4 plays a dual role in breast cancer in mammary tumorigenesis and metastatic progression

  作者：R Sun, J He, Q Xiang, Y Feng, Y Gong 杂志名称：Int J Biol Sci IF：9

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• DIW1 encoding a clade I PP2C phosphatase negatively regulates drought tolerance by dephosphorylating TaSnRK1.1 in wheat

  作者：Wang, Jingyi, et al. 杂志名称：Journal of Integrative Plant Biology IF：11

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• Salvia miltiorrhiza Restrains Reactive Oxygen Species-Associated Pulmonary Fibrosis via Targeting Nrf2-Nox4 Redox Balance

  作者：LY Peng, L An, NY Sun, Y Ma, XW Zhang 杂志名称：The American Journal of Chinese Medicine, Vol IF：4

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• C-Jun/C7ORF41/NF-κB axis mediates hepatic inflammation and lipid accumulation in NAFLD

  作者：FJ Yan, X Wang, SE Wang 杂志名称：Biochemical Journal IF：4

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• MAMDC2, a gene highly expressed in microglia in experimental models of Alzheimers Disease, positively regulates the innate antiviral response during neurotropic virus infection

  作者：Wang Y, Luo W, Wang X, Ma Y, Huang L, Wang Y, 杂志名称： IF：38

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• NTF4 plays a dual role in breast cancer in mammary tumorigenesis and metastatic progression

  作者：R Sun, J He, Q Xiang, Y Feng, Y Gong 杂志名称：Int J Biol Sci IF：9

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• Disruption of Ssp411 causes impaired sperm head formation and male sterility in mice

  作者：Miao Liu, Yanfei Ru, et al 杂志名称：Biochimica et Biophysica Acta (BBA) - General Subjects IF：4

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• A novel inhibitor of nuclear factor kappa-B kinase subunit gamma mutation identified in an incontinentia pigmenti patient with syndromic tooth agenesis

  作者：Sun S, Li F, Liu Y, et al 杂志名称：Arch Oral Biol IF：2

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• MTG8 interacts with LHX6 to specify cortical interneuron subtype identity

  作者：   Asgarian Z,  Oliveira MG,  Stryjewska A 杂志名称：Nature Communications IF：18

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• DIW1 encoding a clade I PP2C phosphatase negatively regulates drought tolerance by dephosphorylating TaSnRK1.1 in wheat

  作者：Wang, Jingyi, et al. 杂志名称：Journal of Integrative Plant Biology IF：11

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• Ginsenoside Rb1 Alleviates Oxidative Low-Density Lipoprotein–Induced Vascular Endothelium Senescence via the SIRT1/Beclin-1/Autophagy Axis

  作者：G Shi, D Liu, B Zhou 杂志名称： Journal of Cardiovascular Pharmacology IF：2

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• Ribosomal L1 domain-containing protein 1 coordinates with HDM2 to negatively regulate p53 in human colorectal Cancer cells

  作者：Li Ding , Zhiping Zhang , Chenhong Zhao 杂志名称：J Exp Clin Cancer Res IF：7

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• hnRNPA2B1 represses the disassembly of arsenite-induced stress granules and is essential for male fertility

  作者：Wang, **aoli, et al 杂志名称：Cell Reports IF：9

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• CTLA-4 Facilitates DNA Damage–Induced Apoptosis by Interacting With PP2A

  作者：Yan Q, Zhang B, Ling X, Zhu B, Mei S, Yang H, Zhang D, Huo J, Zhao Z, 杂志名称：Front Cell Dev Biol IF：5

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• Endothelial deletion of TBK1 contributes to BRB dysfunction via CXCR4 phosphorylation suppression

  作者：Zhao B, Ni Y, Zhang H, et al. 杂志名称：Cell death discovery IF：7

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• A chromosome-level genome assembly for the Silkie chicken resolves complete sequences for key chicken metabolic, reproductive, and immunity genes

  作者：Zhu, F., Yin, Z. T., Zhao, Q. S., Sun, Y. X., Jie 杂志名称：Communications biology IF：6

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• N-Linked Glycosylation and Expression of Duck Plague Virus pUL10 Promoted by pUL49. 5

  作者：C Li, M Wang, A Cheng, Y Wu, B Tian 杂志名称：Microbiology Spectrum IF：4

  查看文献

• SARS-CoV-2 ORF3a positively regulates NF-κB activity by enhancing IKKβ-NEMO interaction

  作者：Nie, Ying, et al. 杂志名称：Virus Research IF：5

  查看文献

• Hsp90 inhibitors directly block HSV-1 DNA replication via inducing degradation of pUL42

  作者：Shurong Qin, Xiao Hu, Xiao Hu 杂志名称：Research Square IF：

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