| 产品英文名称 | CD68 Monoclonal Antibody |
| 产品中文名称 | CD68 单克隆抗体 |
| 别名 | CD68; Macrosialin; Gp110; CD68 |
| 克隆类型 | 单克隆 |
| 检测类型 | IHC-P |
| 反应性 | 小鼠,人,大鼠 |
| 宿主 | 小鼠 |
| 浓度 | 1 mg/ml |
| 免疫原 | 合成多肽 |
| 样本类型 | IHC-P# IF |
| 产品形式 | 液体形式 |
| 基因ID | 968 |
| 目标条带分子量 | 37 |
| 蛋白序列链接 | http://www.uniprot.org/uniprot/P34810 |
| 存储缓冲液 | PBS缓冲液（pH 7.4），含有0.02％叠氮化钠（防腐剂）和50％甘油。 |
| 保存建议 | 自发货之日起，-20°C可稳定保存1年。为最大限度的避免损失，请在打开管盖之前融化抗体并离心。我们建议使用前分装以避免反复冻融。 |
| 运输条件 | 蓝冰运输 |
| 警告 | 本文列出的产品仅供研究使用，不适用于人类或临床诊断。我们产品所推荐应用，不是建议使用我们的产品去违反任何专利或许可证。对于使用本产品可能发生的专利侵权或其他违规行为，我们不承担任何责任。 |
| 其他 | 该抗体可检测内源蛋白 |
| 背景 | CD68 encodes a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family. CD68 molecule primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. It is a type I integral membrane protein with a heavily glycosylated extracellular domain and binds to tissue- and organ-specific lectins or selectins. CD68 molecule is also a member of the scavenger receptor family. Scavenger receptors typically function to clear cellular debris, promote phagocytosis, and mediate the recruitment and activation of macrophages. Alternative splicing results in multiple transcripts encoding different isoforms. |
Fig.1. Immunohistochemical analysis of paraffin-embedded human tonsil tissue. 1, CD68 Monoclonal Antibody was diluted at 1:200 (4°C, overnight). 2, Sodium citrate pH 6.0 was used for antibody retrieval (>98°C, 20min). 3, secondary antibody was diluted at 1:200 (room temperature, 30min). Negative control was used by secondary antibody only.|||ABM40050-2.jpg
作者：Liu Q, Zhou S, Wang X 杂志名称：J Neuroinflammation IF：6
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