产品英文名称 | CREB-1 (phospho Ser133) Polyclonal Antibody |
产品中文名称 | CREB-1 (磷酸化-Ser133)多克隆抗体 |
别名 | CREB1; Cyclic AMP-responsive element-binding protein 1; CREB-1; cAMP-responsive element-binding protein 1 |
克隆类型 | 多克隆 |
检测类型 | IF,ELISA,IP,WB,IHC-P |
反应性 | 小鼠,人,大鼠 |
宿主 | 兔 |
浓度 | 1 mg/ml |
免疫原 | 合成多肽:人源CREB-1 磷酸化位点为中心:S133 |
样本类型 | WB#IF#IHC-P#ELISA#IP |
产品形式 | 液体形式 |
基因ID | 1385 |
蛋白序列链接 | http://www.uniprot.org/uniprot/P16220 |
存储缓冲液 | PBS缓冲液(pH 7.4),含有0.5%BSA(稳定剂),0.02%叠氮化钠(防腐剂)和50%甘油。 |
保存建议 | 自发货之日起,-20°C可稳定保存1年。为最大限度的避免损失,请在打开管盖之前融化抗体并离心。我们建议使用前分装以避免反复冻融。 |
运输条件 | 蓝冰运输 |
警告 | 本文列出的产品仅供研究使用,不适用于人类或临床诊断。我们产品所推荐应用,不是建议使用我们的产品去违反任何专利或许可证。对于使用本产品可能发生的专利侵权或其他违规行为,我们不承担任何责任。 |
其他 | 该抗体可检测内源蛋白 |
背景 | CREB1 encodes a transcription factor (cAMP responsive element binding protein 1) that is a member of the leucine zipper family of DNA binding proteins. cAMP responsive element binding protein 1 binds as a homodimer to the cAMP-responsive element, an octameric palindrome. cAMP responsive element binding protein 1 is phosphorylated by several protein kinases, and induces transcription of genes in response to hormonal stimulation of the cAMP pathway. Alternate splicing of CREB1 results in several transcript variants encoding different isoforms. |
Fig.1. Immunohistochemical analysis of paraffin-embedded human uterus tissue. 1, CREB-1 (phospho Ser133) 多克隆 Antibody was diluted at 1:200 (4°C, overnight). 2, Sodium citrate pH 6.0 was used for antibody retrieval (>98°C, 20min). 3, secondary antibody was diluted at 1:200 (room temperature, 30min). Negative control was used by secondary antibody only.|||ABP0033-2.jpg