| 产品英文名称 | Human/Mouse/Rat TGF-β1 protein, His tag |
| 产品中文名称 | 重组人/小鼠/大鼠转化生长因子β1，His-标签（TGF-β1） |
| 别名 | TGF-beta-1; CED; DPD1; TGFB; TGF-b1; TGFB1; CEDLAP; latency-associated peptide; TGFbeta; TGF-beta 1 protein; transforming growth factor beta-1; TGF-β1; TGF beta1; TGFbeta 1; TGF-beta 1; TGFbeta |
| 序列 | 氨基酸序列来源于：人源 BMP-9/GDF-2(Ser320-Arg429) (Q9UK05) 表达的蛋白片段。 |
| 活性 | Testing in progress. |
| 蛋白长度 | The recombinant Human/Mouse/Rat TGF-β1 consists of 112 amino acids and predicts a molecular mass of 12.9 kDa. |
| 纯度 | > 95 % ，使用SDS-PAGE检测 |
| 特点&优势 | 通过LAL法测定，每微克蛋白里内毒素含量<0.1 EU。 |
| 产品形式 | 冻干粉，冻干缓冲液为无菌的PBS，pH 5.0。 |
| 基因ID | 7040 |
| 蛋白序列链接 | https://www.uniprot.org/uniprotkb/P01137/entry |
| 使用中注意事项 | 开盖使用前，请先离心。本产品为冻干粉，推荐用该产品配套的Reconstitution Buffer进行复溶，且浓度不低于100 µg/mL。客户可根据后续的实验需求，进行进一步的稀释。 |
| 保存建议 | 冻干蛋白应在 -20°C 下保存 1 年。复溶后，在 2°C 至 8°C 下最多可保存 1 周。 在含有载体蛋白或稳定剂的缓冲液（如 0.1% BSA、10%FBS、5%HSA 或 5% 海藻糖溶液）中进一步稀释后，分装的蛋白质应在 -20°C 或 -80°C 下保存 3-15 个月。避免反复冻融循环。 |
| 运输条件 | 冰袋运输（蓝冰） |
| 警告 | 本文列出的产品仅供研究使用，不适用于人类或临床诊断。我们产品所推荐应用，不是建议使用我们的产品去违反任何专利或许可证。对于使用本产品可能发生的专利侵权或其他违规行为，我们不承担任何责任。 |
| 背景 | TGF-β1 is a member of transforming growth factor β(TGF-β) family. Transforming growth factor-β polypeptide family is involved in the regulation of cell processes, including cell division, differentiation, movement, adhesion and death. TGF-β1 regulates many other growth factors positively and negatively. It inhibits the secretion and activity of many other cytokines, including interferon-γ, tumor necrosis factor-α and various interleukins. It can also reduce the expression level of cytokine receptor. TGF-β1 is a multifunctional protein that controls proliferation, differentiation and other functions in many cell types. It plays an important role in bone remodeling, because it is an effective stimulator of osteoblast bone formation, causing the chemotaxis, proliferation and differentiation of directional osteoblasts. Once cells lose their sensitivity to TGF-β1-mediated growth inhibition, autocrine TGF-β signal will promote tumor occurrence. |
Human/Mouse/Rat TGF-β1 protein, His tag
作者：Y Pan, D Zhang, J Zhang, X Liu, J Xu 杂志名称：Allergy, Asthma & Immunology Research IF：4
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