产品英文名称 | Mouse IL-6 Protein |
产品中文名称 | 重组小鼠白介素6(IL-6) |
别名 | interleukin 6, IFN-β2, B-Cell Differentiation Factor (BCDF), BSF-2, HPGF, HSF, MGI-2, IL6 |
表达宿主 | 大肠杆菌 |
种属 | 小鼠 |
序列 | 氨基酸序列来源于:小鼠IL-6 (Phe25-Thr211) (P08505) 表达的蛋白片段。 |
活性 | Testing in progress. |
蛋白长度 | 重组小鼠IL-6 由187个氨基酸组成,预测分子量为21.9 KD。 |
纯度 | > 99 % ,使用SDS-PAGE检测 |
特点&优势 | 通过LAL法测定,每微克蛋白里内毒素含量<0.1 EU。 |
产品形式 | 冻干粉,冻干缓冲液为无菌的20 mM Tris,150 mM NaCl,pH 8.5。 |
基因ID | 16193 |
蛋白序列链接 | https://www.uniprot.org/uniprotkb/P08505/entry |
使用中注意事项 | 开盖使用前,请先离心。本产品为冻干粉,推荐用该产品配套的Reconstitution Buffer进行复溶,且浓度不低于100 µg/mL。客户可根据后续的实验需求,进行进一步的稀释。 |
保存建议 | 本产品为冻干粉形式,建议:将冻干粉产品保存于-20℃以下的干燥环境中。本产品溶解之后,可在4℃保存2-7天,长期使用请置于-20℃以下。为长期保存,推荐添加载体蛋白(0.1% HSA或者BSA),并酌情分装保存,避免反复冻融。 |
运输条件 | 冰袋运输(蓝冰) |
警告 | 本文列出的产品仅供研究使用,不适用于人类或临床诊断。我们产品所推荐应用,不是建议使用我们的产品去违反任何专利或许可证。对于使用本产品可能发生的专利侵权或其他违规行为,我们不承担任何责任。 |
背景 | Interleukin-6 (IL-6) is a pro-inflammatory cytokine that also has an important role in immunity. Mouse IL-6 appears to be directly involved in the responses that occur after infection and injury and may prove to be as important as IL-1 in regulating the acute phase response. Mouse IL-6 is reported to be produced by fibroblasts, activated T cells, activated monocytes or macrophages, and endothelial cells. It acts upon a variety of cells, including fibroblasts, myeloid progenitor cells, T cells, B cells and hepatocytes. IL-6 has a wide variety of biological functions: it plays an essential role in the final differentiation of B-cells into Ig-secreting cells, it induces myeloma and plasmacytoma growth, nerve cells differentiation in hepatocytes, and acute phase reactants. |
Fig.Mouse IL-6 Protein