| 产品英文名称 | Rat IL-6 Protein |
| 产品中文名称 | 重组大鼠白介素-6 |
| 别名 | Interleukin6;IL-6;IL6;IL 6;MGI2-A;MGI2A;HGF;BSF2;HSF;IFNB2;B-Cell Stimulatory Factor-2;Hybridoma/Plasmacytoma Growth Factor;Hepatocyte Stimulating Factor;Cytotoxic T-Cell Differentiation Factor |
| 标签 | 无标签 |
| 表达宿主 | 大肠杆菌 |
| 种属 | 大鼠 |
| 序列 | 氨基酸序列来源于：鼠源IL 6 P20607 (F25-T211) 表达的蛋白片段。 |
| 活性 | Testing in Progress |
| 蛋白长度 | 重组大鼠白细胞介素6 由187个氨基酸组成，预测分子量为21.73 KD。 |
| 纯度 | > 99% ，使用SDS-PAGE检测 |
| 特点&优势 | 通过LAL法测定，每微克蛋白里内毒素含量<1.0 EU。 |
| 产品形式 | 冻干粉，冻干缓冲液为无菌的20 mM Tris，150 mM NaCl，pH 7.4。 |
| 基因ID | M26744.1 |
| 蛋白序列链接 | Il6 - Interleukin-6 - Rattus norvegicus (Rat) | UniProtKB | UniProt |
| 使用中注意事项 | 开盖使用前，请先离心。本产品为冻干粉，推荐用该产品配套的Reconstitution Buffer 10 mM HCl进行复溶，且浓度不低于100 µg/mL。客户可根据后续的实验需求，进行进一步的稀释。 |
| 保存建议 | 本产品为冻干粉形式，建议：将冻干粉产品保存于-20℃以下的干燥环境中。本产品溶解之后，可在4℃保存2-7天，长期使用请置于-20℃以下。为长期保存，推荐添加载体蛋白（0.1% HAS/BSA或10%FBS），并酌情分装保存，避免反复冻融。 |
| 运输条件 | 冰袋运输（蓝冰） |
| 警告 | 本文列出的产品仅供研究使用，不适用于人类或临床诊断。我们产品所推荐应用，不是建议使用我们的产品去违反任何专利或许可证。对于使用本产品可能发生的专利侵权或其他违规行为，我们不承担任何责任。 |
| 背景 | Interleukin-6 (IL-6) is a multifunctional α-helical cytokine that regulates cell growth and differentiation of various tissues, which is known particularly for its role in the immune response and acute phase reactions. IL-6 protein is secreted by a variety of cell types including T cells and macrophages as a phosphorylated and variably glycosylated molecule. It exerts actions through its heterodimeric receptor composed of IL-6R that lacks the tyrosine/kinase domain and binds IL-6 with low affinity, and ubiquitously expressed glycoprotein 130 (gp130) that binds the IL-6. IL-6R complex with high affinity and thus transduces signals. IL-6 is also involved in hematopoiesis, bone metabolism, and cancer progression, and has been defined as an essential role in directing the transition from innate to acquired immunity. |
Fig.Rat IL-6 Protein
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