产品英文名称 | Human/Mouse/Rat GDF11 Protein, His tag |
产品中文名称 | 重组人/小鼠/大鼠生长分化因子11,His-标签(GDF11) |
别名 | bone morphogenetic protein 11, Growth/Differentiation Factor-11, GDF-11, BMP11 |
序列 | 氨基酸序列来源于:人/小鼠/大鼠源GDF-11(Asn299-Ser407)(O95390)表达的蛋白片段。 |
活性 | Testing in Progress |
蛋白长度 | 重组人/小鼠/大鼠GDF-11由109个氨基酸组成,预测分子量为12.6KD。 |
纯度 | > 95 % ,使用SDS-PAGE检测 |
特点&优势 | 通过LAL法测定,每微克蛋白里内毒素含量<0.1 EU。 |
产品形式 | 冻干粉,冻干缓冲液为无菌的20 mM Tris,50 mM NaCl,pH 9.0。 |
基因ID | 10220 |
蛋白序列链接 | https://www.uniprot.org/uniprotkb/O95390/entry#sequences |
使用中注意事项 | 开盖使用前,请先离心。本产品为冻干粉,推荐用该产品配套的Reconstitution Buffer进行复溶,且浓度不低于105 µg/mL。客户可根据后续的实验需求,进行进一步的稀释。 |
保存建议 | 本产品为冻干粉形式,建议:将冻干粉产品保存于-20℃以下的干燥环境中。本产品溶解之后,可在4℃保存2-7天,长期使用请置于-20℃以下。为长期保存,推荐添加载体蛋白(0.1% HSA或者BSA),并酌情分装保存,避免反复冻融。 |
运输条件 | 冰袋运输(蓝冰) |
警告 | 本文列出的产品仅供研究使用,不适用于人类或临床诊断。我们产品所推荐应用,不是建议使用我们的产品去违反任何专利或许可证。对于使用本产品可能发生的专利侵权或其他违规行为,我们不承担任何责任。 |
背景 | Vascular GDF-11 is a myostatin-homologous protein that acts as an inhibitor of nerve tissue growth. GDF-11 has been shown to suppress neurogenesis through a myostatin-like pathway, which involves the arrest of the progenitor cell cycle in the G1 phase. Similarities between myostatin and GDF-11, which are 90% identical in their amino acid sequence, suggest that the regulatory mechanisms responsible for maintaining proper tissue size during neural and muscular development might be the same. Recombinant Human/Murine/Rat GDF-11 is highly homologous to myostatin/GDF-8, sharing 90% amino acid sequence identity |
Fig.Human Mouse Rat GDF11 Protein, His tag