| 产品英文名称 | Human PDGF-BB protein |
| 产品中文名称 | 重组人血小板衍生生长因子BB(PDGF-BB) |
| 标签 | 无标签 |
| 表达宿主 | 大肠杆菌 |
| 种属 | 人 |
| 活性 | Measured in a cell proliferation assay using BaIb/c 3T3. The ED50 for this effect is typically 2.588 ng/mL. The specific activity of recombinant Human PDGF-BB is approximately >3.86 x 105 IU/mg. |
| 纯度 | > 98 % as determined by SDS-PAGE |
| 产品形式 | 冻干粉 |
| 基因ID | 5155 |
| 保存建议 | 建议收到货后避光保存于-20°C,有效期为12个月。 |
| 运输条件 | 冰袋运输(蓝冰) |
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| 背景 | Platelet derived growth factor (PDGF) is a potent mitogen and chemoattractant for mesenchymal and osteogenic cells and stimulates angiogenic molecules which play an essential role in bone regeneration. PDGF-BB is a member of PDGF family, which promotes cell proliferation, survival and migration, through binding to the tyrosine kinase PDGF receptor. PDGF-BB exerts beneficial effects on haemorrhagic shock, which are closely related to targeting CX43 to improve vascular reactivity and haemodynamics. PDGF-BB functions in corporal cavernosum smooth muscle cells (CCSMCs) via binding to PDGFR. |
Fig.PRP1958 - 重组人血小板衍生生长因子BB(PDGF-BB)