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重组小鼠粒细胞-巨噬细胞集落刺激因子(GM-CSF)

Mouse GM-CSF protein

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Mouse GM-CSF protein
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商品信息

产品英文名称 Mouse GM-CSF protein
产品中文名称 重组小鼠粒细胞-巨噬细胞集落刺激因子(GM-CSF)
别名 CSF; CSF2; CSF-2; GMCSF; GM-CSF;colony stimulating factor 2 (granulocyte-macrophage); granulocyte-macrophage colony-stimulating factor; Colony-stimulating factor;  GMCSF, granulocyte-macrophage colony stimulating factor; molgramostin; Sargramostim, MGC131935; MGC138897; Molgramostim;

商品属性

分子GM-CSF
标签无标签
种属小鼠
序列Amino acid sequence derived from Mouse GM-CSF protein isoform (P01587,Met1-Lys141) was expressed.
活性检测进行中
蛋白长度重组小鼠GM-CSF蛋白由128个氨基酸组成,预测分子量为14.6 kDa。 在还原条件下,SDS-PAGE中小鼠GM-CSF蛋白的表观分子量约为15-25 kDa。
纯度≥ 90 % ,使用SDS-PAGE检测
特点&优势采用 LAL 法检测,每 1 μg 蛋白质中的 EU 含量小于 1.0。
产品形式冻干粉,冻干缓冲液为无菌的 PBS,pH 7.4。
基因ID12981
蛋白序列链接http://www.uniprot.org/uniprot/P01587
使用中注意事项开盖使用前,请先离心。本产品为冻干粉,推荐用该产品配套的Reconstitution Buffer进行复溶,且浓度不低于100 µg/mL。客户可根据后续的实验需求,进行进一步的稀释。
保存建议本产品为冻干粉形式,建议:将冻干粉的重组小鼠粒细胞-巨噬细胞集落刺激因子(GM-CSF)产品保存于-20℃以下的干燥环境中。本产品溶解之后,可在4℃保存2-7天,长期使用请置于-20℃以下。为长期保存,推荐添加载体蛋白(0.1% HSA或者BSA),并酌情分装保存,避免反复冻融。
运输条件常温运输
警告本文列出的产品仅供研究使用,不适用于人类或临床诊断。我们产品所推荐应用,不是建议使用我们的产品去违反任何专利或许可证。对于使用本产品可能发生的专利侵权或其他违规行为,我们不承担任何责任。

附加信息

背景The granulocyte-macrophage colony-stimulating factor (GM-CSF) is an important hematopoietic growth factor and immune modulator. GM-CSF also has profound effects on the functional activities of various circulating leukocytes. It is produced by a variety of cell types including T cells, macrophages, endothelial cells and fibroblasts upon receiving immune stimuli. Although GM-CSF is produced locally, it can act in a paracrine fashion to recruit circulating neutrophils, monocytes and lymphocytes to enhance their functions in host defense. GM-CSF was initially classified as a hematopoietic growth factor. However, unlike its close relatives macrophage CSF (M-CSF) and granulocyte CSF (G-CSF), the majority of myeloid cells do not require GM-CSF for steady-state myelopoiesis. Instead, in inflammation, GM-CSF serves as a communication conduit between tissue-invading lymphocytes and myeloid cells. Even though lymphocytes are in all likelihood the instigators of chronic inflammatory disease, GM-CSF-activated phagocytes are well equipped to cause tissue damage.

图片及说明

Fig.SDS-PAGE analysis of Mouse GM-CSF protei.

Fig.SDS-PAGE analysis of Mouse GM-CSF protei.

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