产品英文名称 | AMPKα1/2 (phospho Thr183/172) Polyclonal Antibody |
产品中文名称 | AMPKα1/2 (磷酸化-Thr183/172)多克隆抗体 |
别名 | PRKAA1; AMPK1; 5'-AMP-activated protein kinase catalytic subunit alpha-1; AMPK subunit alpha-1; Acetyl-CoA carboxylase kinase; ACACA kinase; Hydroxymethylglutaryl-CoA reductase kinase; HMGCR kinase; Tau-protein kinase PRKAA1; PRKAA2; AMPK; |
克隆类型 | 多克隆 |
检测类型 | IHC-P,WB,ELISA,IF |
反应性 | 大鼠,猪,小鼠,人,猴 |
宿主 | 兔 |
浓度 | 1 mg/ml |
免疫原 | 合成多肽:人源AMPKα1/2 磷酸化位点为中心:T183/172 |
样本类型 | WB#IF#IHC-P#ELISA |
产品形式 | 液体形式 |
基因ID | 5562/5563 |
蛋白序列链接 | http://www.uniprot.org/uniprot/Q13131 |
存储缓冲液 | PBS缓冲液(pH 7.4),含有0.5%BSA(稳定剂),0.02%叠氮化钠(防腐剂)和50%甘油。 |
保存建议 | 自发货之日起,-20°C可稳定保存1年。为最大限度的避免损失,请在打开管盖之前融化抗体并离心。我们建议使用前分装以避免反复冻融。 |
运输条件 | 蓝冰运输 |
警告 | 本文列出的产品仅供研究使用,不适用于人类或临床诊断。我们产品所推荐应用,不是建议使用我们的产品去违反任何专利或许可证。对于使用本产品可能发生的专利侵权或其他违规行为,我们不承担任何责任。 |
其他 | 该抗体可检测内源蛋白 |
背景 | Protein kinase AMP-activated catalytic subunit alpha 1 encoded by PRKAA1 belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed. |
Fig. Western Blot analysis of mouse lung cells using primary antibody diluted at 1:1000 (4°C overnight).
作者:Xu Y, Lu Y, Xu R 杂志名称:Brain Research IF:4