| 产品英文名称 | AMPKα1/2 Polyclonal Antibody |
| 产品中文名称 | AMPKα1/2多克隆抗体 |
| 别名 | PRKAA1; AMPK1; 5'-AMP-activated protein kinase catalytic subunit alpha-1; AMPK subunit alpha-1; Acetyl-CoA carboxylase kinase; ACACA kinase; Hydroxymethylglutaryl-CoA reductase kinase; HMGCR kinase; Tau-protein kinase PRKAA1; PRKAA2; AMPK; |
| 克隆类型 | 多克隆 |
| 检测类型 | ELISA,WB,IHC-P |
| 反应性 | 人,猴,大鼠,小鼠 |
| 宿主 | 兔 |
| 浓度 | 1 mg/ml |
| 免疫原 | 合成多肽：人源AMPKα1/2 非磷酸化位点为中心：T183/172 |
| 样本类型 | WB#IHC-P#ELISA |
| 产品形式 | 液体形式 |
| 基因ID | 5562/5563 |
| 蛋白序列链接 | http://www.uniprot.org/uniprot/Q13131 |
| 存储缓冲液 | PBS缓冲液（pH 7.4），含有0.5%BSA（稳定剂），0.02％叠氮化钠（防腐剂）和50％甘油。 |
| 保存建议 | 自发货之日起，-20°C可稳定保存1年。为最大限度的避免损失，请在打开管盖之前融化抗体并离心。我们建议使用前分装以避免反复冻融。 |
| 运输条件 | 蓝冰运输 |
| 警告 | 本文列出的产品仅供研究使用，不适用于人类或临床诊断。我们产品所推荐应用，不是建议使用我们的产品去违反任何专利或许可证。对于使用本产品可能发生的专利侵权或其他违规行为，我们不承担任何责任。 |
| 其他 | 该抗体可检测内源蛋白 |
| 背景 | Protein kinase AMP-activated catalytic subunit alpha 1 encoded by PRKAA1 belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed. |
Fig.1. Western Blot analysis of various cells using AMPKα1/2 多克隆 Antibody diluted at 1:500.|||ABP0060-2.jpg
作者：Wang S, Mobasheri A, Zhang Y, Wang Y, Dai T, Zhang Z 杂志名称：Inflammopharmacology IF：3
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