| 产品英文名称 | Claudin-1 Polyclonal Antibody |
| 产品中文名称 | Claudin-1多克隆抗体 |
| 别名 | CLDN1; CLD1; SEMP1; Claudin-1; Senescence-associated epithelial membrane protein |
| 克隆类型 | 多克隆 |
| 检测类型 | IHC-P,WB,ELISA,IF |
| 反应性 | 小鼠,人,大鼠 |
| 宿主 | 兔 |
| 浓度 | 1 mg/ml |
| 免疫原 | 合成多肽：人源蛋白的C末端，Claudin-1，AA：140-220 |
| 样本类型 | WB#IF#IHC-P#ELISA |
| 产品形式 | 液体形式 |
| 基因ID | 9076 |
| 蛋白序列链接 | http://www.uniprot.org/uniprot/O95832 |
| 存储缓冲液 | PBS缓冲液（pH 7.4），含有0.5%BSA（稳定剂），0.02％叠氮化钠（防腐剂）和50％甘油。 |
| 保存建议 | 自发货之日起，-20°C可稳定保存1年。为最大限度的避免损失，请在打开管盖之前融化抗体并离心。我们建议使用前分装以避免反复冻融。 |
| 运输条件 | 蓝冰运输 |
| 警告 | 本文列出的产品仅供研究使用，不适用于人类或临床诊断。我们产品所推荐应用，不是建议使用我们的产品去违反任何专利或许可证。对于使用本产品可能发生的专利侵权或其他违规行为，我们不承担任何责任。 |
| 其他 | 该抗体可检测内源蛋白 |
| 背景 | Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by CLDN1, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. Loss of function mutations result in neonatal ichthyosis-sclerosing cholangitis syndrome. |
Fig. Western Blot analysis of various cells using Claudin-1 多克隆 Antibody diluted at 1:1000.
作者：Li Y, Liu H, Qi H, Tang W, Zhang C, Liu Z, Liu Y, Wei X, Kong Z, Jia S, Du B, Yuan J, Wang C, Li M 杂志名称：Biomed Pharmacother IF：5
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