产品英文名称 | E-cadherin Polyclonal Antibody |
产品中文名称 | E-cadherin多克隆抗体 |
别名 | CDH1; CDHE; UVO; Cadherin-1; CAM 120/80; Epithelial cadherin; E-cadherin; Uvomorulin; CD antigen CD324; CDH2; CDHN; NCAD; Cadherin-2; CDw325; Neural cadherin; N-cadherin; CD antigen CD325; CDH3; CDHP; Cadherin-3; Placental cadherin; P-cadhe |
克隆类型 | 多克隆 |
检测类型 | WB,ELISA,IF,IHC-P |
反应性 | 人,大鼠,小鼠 |
宿主 | 兔 |
浓度 | 1 mg/ml |
免疫原 | 合成多肽:人源蛋白的C末端,E-cadherin,AA:810-890 |
样本类型 | WB#IF#IHC-P#ELISA |
产品形式 | 液体形式 |
基因ID | 999/1000/1001/1002 |
蛋白序列链接 | http://www.uniprot.org/uniprot/P12830 |
存储缓冲液 | PBS缓冲液(pH 7.4),含有0.5%BSA(稳定剂),0.02%叠氮化钠(防腐剂)和50%甘油。 |
保存建议 | 自发货之日起,-20°C可稳定保存1年。为最大限度的避免损失,请在打开管盖之前融化抗体并离心。我们建议使用前分装以避免反复冻融。 |
运输条件 | 蓝冰运输 |
警告 | 本文列出的产品仅供研究使用,不适用于人类或临床诊断。我们产品所推荐应用,不是建议使用我们的产品去违反任何专利或许可证。对于使用本产品可能发生的专利侵权或其他违规行为,我们不承担任何责任。 |
其他 | 该抗体可检测内源蛋白 |
背景 | CDH1 encodes a classical cadherin of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion protein is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in CDH1 are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function of this gene is thought to contribute to cancer progression by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. CDH1 is present in a gene cluster with other members of the cadherin family on chromosome 16. |
Fig.1. Western Blot analysis of various cells using E-cadherin 多克隆 Antibody diluted at 1:2000.|||ABP0083-2.jpg
作者:W Liang, J Liu, H Wu, X Qiao, X Lu 杂志名称:Oncology letters IF:2
作者:Hossain AJ, Islam R, Kim JG 杂志名称:Biomedicines . IF:5