产品英文名称 | Bax Polyclonal Antibody |
产品中文名称 | BCL2关联X蛋白多克隆抗体 |
别名 | BAX; BCL2L4; Apoptosis regulator BAX; Bcl-2-like protein 4; Bcl2-L-4 |
克隆类型 | 多克隆 |
检测类型 | WB |
反应性 | 大鼠,小鼠,人 |
宿主 | 兔 |
浓度 | 1 mg/ml |
免疫原 | 合成多肽:来源于中间区域的人源蛋白Bax. 氨基酸序列为: 10-90 |
样本类型 | WB# IHC-P# IF# ELISA |
产品形式 | 液体形式 |
基因ID | 581 |
蛋白序列链接 | http://www.uniprot.org/uniprot/Q07812 |
存储缓冲液 | 含有50%甘油,0.5%BSA和0.02%叠氮化钠的PBS缓冲液。 |
保存建议 | 自发货之日起,-20°C可稳定保存1年。为最大限度的避免损失,请在打开管盖之前融化抗体并离心。我们建议使用前分装以避免反复冻融。 |
运输条件 | 蓝冰运输 |
警告 | 本文列出的产品仅供研究使用,不适用于人类或临床诊断。我们产品所推荐应用,不是建议使用我们的产品去违反任何专利或许可证。对于使用本产品可能发生的专利侵权或其他违规行为,我们不承担任何责任。 |
其他 | 该抗体可检测内源蛋白 |
背景 | The protein encoded by BAX belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein (BCL2 associated X, apoptosis regulator) forms a heterodimer with BCL2, and functions as an apoptotic activator. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC, which leads to the loss in membrane potential and the release of cytochrome c. The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis. Multiple alternatively spliced transcript variants, which encode different isoforms, have been reported for BAX. |
Fig.1. Western Blot analysis of various cells using Bax Polyclonal Antibody.|||Abp50752-2.jpg
作者:Cheng‐Liang Yang, Xiao‐Li Zheng, Ke Ye, et al 杂志名称:J Cell Physiol IF:4
作者:LanLing, Shan-HongZhang, et al 杂志名称:Biomedicine & Pharmacotherapy IF:4
作者: Tang L, Yu J, Zhuge S 杂志名称:TOXICOLOGY IF:5
作者:Guang‐Cai Li, Xu‐Ling Qin, Huai‐Hua Song, et al 杂志名称: J Cell Physiol IF:4
作者:Feng‐Hua Yuan, You‐Lian Chen, Ying Zhao, et al 杂志名称:J Cell Physiol IF:4
作者:E Jin, Y Pei, T Liu, et al 杂志名称:Food and Agricultural Immunology IF:2