微管蛋白α多克隆抗体

Tubulin α Polyclonal Antibody

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价格:¥739

规格:

739/30 μL
1616/100 μL
2658/200 μL

数量:

货期:期货（3天内发货）

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产品概述
使用说明
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文献引用(2)
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商品信息

产品英文名称	Tubulin α Polyclonal Antibody
产品中文名称	微管蛋白α多克隆抗体
别名	TUBA1A; TUBA3; Tubulin alpha-1A chain; Alpha-tubulin 3; Tubulin B-alpha-1; Tubulin alpha-3 chain; TUBA1B; Tubulin alpha-1B chain; Alpha-tubulin ubiquitous; Tubulin K-alpha-1; Tubulin alpha-ubiquitous chain

商品属性

克隆类型	多克隆
检测类型	WB
反应性	人,大鼠,小鼠
宿主	兔
浓度	1 mg/ml
免疫原	合成多肽：来源于C端的人源蛋白Tubulin α. 氨基酸序列为： 380-460
样本类型	WB# IHC-p# IF# ELISA
产品形式	液体形式
基因ID	7846/10376
目标条带分子量	50
蛋白序列链接	http://www.uniprot.org/uniprot/Q71U36
存储缓冲液	含有50％甘油，0.5％BSA和0.02％叠氮化钠的PBS缓冲液。
保存建议	自发货之日起，-20°C可稳定保存1年。为最大限度的避免损失，请在打开管盖之前融化抗体并离心。我们建议使用前分装以避免反复冻融。
运输条件	蓝冰运输
警告	本文列出的产品仅供研究使用，不适用于人类或临床诊断。我们产品所推荐应用，不是建议使用我们的产品去违反任何专利或许可证。对于使用本产品可能发生的专利侵权或其他违规行为，我们不承担任何责任。
其他	该抗体可检测内源蛋白

附加信息

背景

Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulins. TUBA1A encoding these microtubule constituents belong to the tubulin superfamily, which is composed of six distinct families. Genes from the alpha, beta and gamma tubulin families are found in all eukaryotes. The alpha and beta tubulins represent the major components of microtubules, while gamma tubulin plays a critical role in the nucleation of microtubule assembly. There are multiple alpha and beta tubulin genes, which are highly conserved among species. This gene encodes alpha tubulin and is highly similar to the mouse and rat Tuba1 genes. Northern blotting studies have shown that the gene expression is predominantly found in morphologically differentiated neurologic cells. This gene is one of three alpha-tubulin genes in a cluster on chromosome 12q. Mutations in this gene cause lissencephaly type 3 (LIS3) - a neurological condition characterized by microcephaly, mental retardation, and early-onset epilepsy and caused by defective neuronal migration. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

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