产品英文名称 | IL-1β Polyclonal Antibody |
产品中文名称 | 白细胞介素1β多克隆抗体 |
别名 | IL1B; IL1F2; Interleukin-1 beta; IL-1 beta; Catabolin |
克隆类型 | 多克隆 |
检测类型 | WB |
反应性 | 小鼠,人,大鼠 |
宿主 | 兔 |
浓度 | 1 mg/ml |
免疫原 | 合成多肽:来源于中间区域的人源蛋白IL-1β. |
样本类型 | WB# IHC-p# ELISA |
产品形式 | 液体形式 |
基因ID | 3553 |
目标条带分子量 | 17kd, 35kd |
蛋白序列链接 | http://www.uniprot.org/uniprot/P01584 |
存储缓冲液 | 含有50%甘油,0.5%BSA和0.02%叠氮化钠的PBS缓冲液。 |
保存建议 | 自发货之日起,-20°C可稳定保存1年。为最大限度的避免损失,请在打开管盖之前融化抗体并离心。我们建议使用前分装以避免反复冻融。 |
运输条件 | 蓝冰运输 |
警告 | 本文列出的产品仅供研究使用,不适用于人类或临床诊断。我们产品所推荐应用,不是建议使用我们的产品去违反任何专利或许可证。对于使用本产品可能发生的专利侵权或其他违规行为,我们不承担任何责任。 |
其他 | 该抗体可检测内源蛋白 |
背景 | Interleukin-1 beta encoded by IL1B is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. |
Fig.1. Western Blot analysis of ES-2 (1, U87 (2, PC-3 (3, SHSY5Y (4, mouse liver (5, diluted at 1:2000.|||ABP52932-2.jpg
作者:H Liu, Y Li, S Sun, Q Xin 杂志名称:Nature Communications IF:18
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作者:XX Xu, RX Shi, Y Fu, JL Wang, X Tong 杂志名称:Neural Regeneration Research IF:6
作者:Liu Zi , Wencheng Zhou, Jiake Xu 杂志名称:Int J Nanomedicine. IF:5