产品英文名称 | PPAR-α Polyclonal Antibody |
产品中文名称 | 过氧化物酶体增殖活化受体α多克隆抗体 |
别名 | PPARA; NR1C1; PPAR; Peroxisome proliferator-activated receptor alpha; PPAR-alpha; Nuclear receptor subfamily 1 group C member 1 |
克隆类型 | 多克隆 |
检测类型 | WB |
反应性 | 人,大鼠,小鼠 |
宿主 | 兔 |
浓度 | 1 mg/ml |
免疫原 | 合成多肽:人源蛋白PPAR-α,非磷酸化多肽,中心氨基酸为S21. |
样本类型 | WB# IHC-p# IF# ELISA |
产品形式 | 液体形式 |
基因ID | 5465 |
目标条带分子量 | 52 |
蛋白序列链接 | http://www.uniprot.org/uniprot/Q07869 |
存储缓冲液 | 含有50%甘油,0.5%BSA和0.02%叠氮化钠的PBS缓冲液。 |
保存建议 | 自发货之日起,-20°C可稳定保存1年。为最大限度的避免损失,请在打开管盖之前融化抗体并离心。我们建议使用前分装以避免反复冻融。 |
运输条件 | 蓝冰运输 |
警告 | 本文列出的产品仅供研究使用,不适用于人类或临床诊断。我们产品所推荐应用,不是建议使用我们的产品去违反任何专利或许可证。对于使用本产品可能发生的专利侵权或其他违规行为,我们不承担任何责任。 |
其他 | 该抗体可检测内源蛋白 |
背景 | Peroxisome proliferators include hypolipidemic drugs, herbicides, leukotriene antagonists, and plasticizers; this term arises because they induce an increase in the size and number of peroxisomes. Peroxisomes are subcellular organelles found in plants and animals that contain enzymes for respiration and for cholesterol and lipid metabolism. The action of peroxisome proliferators is thought to be mediated via specific receptors, called PPARs, which belong to the steroid hormone receptor superfamily. PPARs affect the expression of target genes involved in cell proliferation, cell differentiation and in immune and inflammation responses. Three closely related subtypes (alpha, beta/delta, and gamma) have been identified. PPARA (peroxisome proliferator activated receptor alpha) encodes the subtype PPAR-alpha, which is a nuclear transcription factor. Multiple alternatively spliced transcript variants have been described for PPARA, although the full-length nature of only two has been determined. |
Fig.1. Western Blot analysis of 3T3 cells using PPAR-α Polyclonal Antibody.|||ABP55667-2.jpg
作者:Mi A, Hu Q, Liu Y 杂志名称:Food & Function IF:6
作者:Mi, Ai, et al 杂志名称:Food & Function IF:6
作者:Mi A, Hu Q, Liu Y, et al 杂志名称:Food & Function IF:6
作者:Zhang Y, Li T 杂志名称:J Transl Med IF:4