产品英文名称 | Tau (Acetyl Lys174) Polyclonal Antibody |
产品中文名称 | 微管关联蛋白Tau多克隆抗体 |
别名 | Microtubule-associated protein tau; Neurofibrillary tangle protein; Paired helical filament-tau; PHF-tau |
克隆类型 | 多克隆 |
检测类型 | WB |
反应性 | 大鼠,小鼠,人 |
宿主 | 兔 |
浓度 | 1 mg/ml |
免疫原 | 合成多肽:来源于人源 Tau (Acetyl Lys174) 蛋白,氨基酸序列为:174 |
样本类型 | WB# ELISA |
产品形式 | 液体形式 |
基因ID | 4137 |
目标条带分子量 | 50-85 |
蛋白序列链接 | http://www.uniprot.org/uniprot/P10636 |
存储缓冲液 | PBS缓冲液(pH 7.4),含有0.02%叠氮化钠(防腐剂)和50%甘油。 |
保存建议 | 自发货之日起,-20°C可稳定保存1年。为最大限度的避免损失,请在打开管盖之前融化抗体并离心。我们建议使用前分装以避免反复冻融。 |
运输条件 | 蓝冰运输 |
警告 | 本文列出的产品仅供研究使用,不适用于人类或临床诊断。我们产品所推荐应用,不是建议使用我们的产品去违反任何专利或许可证。对于使用本产品可能发生的专利侵权或其他违规行为,我们不承担任何责任。 |
其他 | 该抗体可检测内源蛋白 |
背景 | MAPT encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy. MAPT (Microtubule Associated Protein Tau) is a Protein Coding gene. Diseases associated with MAPT include Pick Disease and Supranuclear Palsy, Progressive. Among its related pathways are Alzheimers Disease Pathway and Reelin signaling pathway. |
Fig.1. Western blot analysis of KB Hela lysate, antibody was diluted at 1:1000. HRP, Goat Anti-Rabbit IgG (Cat #: A21020) secondary antibody was diluted at 1:20000.
作者:Shi YH, Zhang XL, Ying PJ, Wu ZQ, Lin LL, Chen W, Zheng GQ, Zhu WZ, 杂志名称:Front Pharmacol IF:4